SDZ285428
SDZ285428 is a CYP51 inhibitor. SDZ285428 inhibits Trypanosoma cruzi (TC) CYP51 with I/E2 Trypanosoma brucei (TB) CYP51 with I/E2 [1].
Product Specifications
CAS Number
[174262-13-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cytochrome P450; Fungal; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sdz285428.html
Concentration
10mM
Purity
98.00
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C2=CC=C(Cl)C=C2)C=C1)NCC(N3C=CN=C3)C4=CC=CC=C4
Molecular Formula
C24H20ClN3O
Molecular Weight
401.89
Precautions
H302, H315, H319, H335
References & Citations
[1]Lepesheva GI, et al. CYP51: A major drug target in the cytochrome P450 superfamily. Lipids. 2008 Dec;43 (12) :1117-25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP51; Trypanosoma
Available Sizes
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