Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-SERCA3 ATPase/ATP2A3 Antibody Picoband® (FITC Conjugate)

Boster Bio Anti-SERCA3 ATPase/ATP2A3 Antibody catalog # RP1055. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, also known as SERCA3, is anenzyme that in humans is encoded by the ATP2A3 gene. It is mapped to 17p13.2. This gene encodes one of the SERCA Ca2+-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of cells. ATP2A3 expression was originally described as non-muscular, but was recently observed in cardiomyocyte. What’s more, the expression of ATP2A3 was significantly reduced or lost in colon carcinomas compared with normal colonic epithelial cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.

Synonyms

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3;SERCA3;SR Ca (2+)-ATPase 3;3.6.3.8;Calcium pump 3;ATP2A3;

Gene Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

UniProt

Q93084

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ATP2A3, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.

Clonality

Polyclonal

Tissue Specificity

Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. Expressed in cell lineages of hematopoietic, epithelial, or embryonic origin and also expressed in several cancer cell lines. .

Applications

IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=RP1055

Product MSDS

https://www.bosterbio.com/msds?sku=RP1055

Fragment

Rabbit IgG

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, Human, By Heat<br>Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human<br>

Subcellular Location

Nucleus membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein .

Sequence Similarities

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.

Protein Name

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Gpr65 Rat shRNA Lentiviral Particle (Locus ID 299242)
TL705325V 500 µL Each

Gpr65 Rat shRNA Lentiviral Particle (Locus ID 299242)

Ask
View Details
Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody
abx032609-01 80 µL

Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody

Ask
View Details
Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody
abx032609-02 400 µL

Killer Cell Immunoglobulin-Like Receptor 2DS3 (KIR2DS3) Antibody

Ask
View Details
Fish Otolin 1 (OTOL1) ELISA Kit
MBS9354606 Inquire

Fish Otolin 1 (OTOL1) ELISA Kit

Ask
View Details
Cfdp1 (NM_011801) Mouse Untagged Clone
MC205683 10 µg

Cfdp1 (NM_011801) Mouse Untagged Clone

Ask
View Details
NUMBL Polyclonal Antibody
ANT-13559-100ug 100 µg

NUMBL Polyclonal Antibody

Ask
View Details