Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TFPI Antibody Picoband® (HRP Conjugate)

Boster Bio Anti-TFPI Antibody Picoband® catalog # A01052. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

TFPI (Tissue factor pathway inhibitor) also known as EPI, LACI, TFI and TFPT1 is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM. The gene for TFPI is located on chromosome 2q31-q32.1, and has nine exons which span 70 kb. TFPI has a relative molecular mass of 34,000 to 40,000 depending on the degree of proteolysis of the C-terminal region.

Synonyms

Tissue factor pathway inhibitor;TFPI;Extrinsic pathway inhibitor;EPI;Lipoprotein-associated coagulation inhibitor;LACI;TFPI;LACI, TFPI1;

Gene Name

Tissue factor pathway inhibitor

UniProt

P10646

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TFPI recombinant protein (Position: N253-M304). Human TFPI shares 51.1% and 53.2% amino acid (aa) sequence identity with mouse and rat TFPI, respectively.

Clonality

Polyclonal

Tissue Specificity

Mostly in endothelial cells.

Applications

WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Inhibits factor X (X (a)) ly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01052

Product MSDS

https://www.bosterbio.com/msds?sku=A01052

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human<br>

Subcellular Location

Isoform Alpha: Secreted.

Protein Name

Tissue factor pathway inhibitor

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Anti-CLN8 antibody
STJ119214 100 µl

Anti-CLN8 antibody

Ask
View Details
Myosin VIIB (MYO7B) Human ELISA Kit
F1940 96 Tests

Myosin VIIB (MYO7B) Human ELISA Kit

Ask
View Details
Guinea Pig Glia Maturation Factor β ELISA Kit
E05G0207-01 48 Well

Guinea Pig Glia Maturation Factor β ELISA Kit

Ask
View Details
Guinea Pig Glia Maturation Factor β ELISA Kit
E05G0207-02 96 Well

Guinea Pig Glia Maturation Factor β ELISA Kit

Ask
View Details
Mouse Lrig3 activation kit by CRISPRa
GA216482 1 Kit

Mouse Lrig3 activation kit by CRISPRa

Ask
View Details
EIF4BP1 AAV Vector (Human) (CMV)
19150101 1 μg

EIF4BP1 AAV Vector (Human) (CMV)

Ask
View Details