Cyclo (CLLFVY)
Cyclo (CLLFVY) is a cyclic peptide inhibitor of HIF-1 that targets the HIF-1α PAS-B domain, blocking dimerization and downstream gene expression (e.g., VEGF, CAIX) with IC50 values of 19 μM (U2OS) and 16 μM (MCF-7) . It is a research tool for studying hypoxia signaling and oncology in cellular models.
Product Specifications
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Molecular Weight
738.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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