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Cyclo (CLLFVY)

Cyclo (CLLFVY) is a cyclic peptide inhibitor of HIF-1 that targets the HIF-1α PAS-B domain, blocking dimerization and downstream gene expression (e.g., VEGF, CAIX) with IC50 values of 19 μM (U2OS) and 16 μM (MCF-7) . It is a research tool for studying hypoxia signaling and oncology in cellular models.

Product Specifications

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Molecular Weight

738.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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