Anti-Calcitonin/CALCA Antibody (HRP Conjugate)
Boster Bio Anti-Calcitonin/CALCA Antibody Picoband® catalog # PB9936. Tested in IHC applications. This antibody reacts with Human.
Product Specifications
Background
Calcitonin, also known as CALCA, is a peptide hormone synthesized by the parafollicular cells of the thyroid. It is mapped to 11p15.2. Calcitonin belongs to the calcitonin-like protein family. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
Calcitonin gene-related peptide 1;Alpha-type CGRP;Calcitonin gene-related peptide I;CGRP-I;CALCA;CALC1;
Gene Name
Calcitonin gene-related peptide 1
UniProt
P06881
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Calcitonin, different from the related mouse and rat sequences by four amino acids.
Clonality
Polyclonal
Tissue Specificity
Plasma.
Applications
IHC
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Lyophilized
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. .
Storage Conditions
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Applications Notes
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat <br>
Subcellular Location
Secreted.
Protein Name
Calcitonin gene-related peptide 1
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