Masupirdine (mesylate)
Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally active, and brain-penetrating 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Masupirdine mesylate has pro-cognitive effects on all stages of cognition (acquisition, consolidation, and retention), and can reverse Scopolamine , MK-801 (HY-15084B) -induced and aging-related memory deficits. Masupirdine mesylate can be used in the research of Alzheimer's disease[1][2].
Product Specifications
CAS Number
1791396-46-7
Product Name Alternative
SUVN-502 (mesylate)
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/masupirdine-mesylate.html
Purity
99.62
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CS(=O)(O)=O.O=S(N1C2=CC=C(OC)C=C2C(CN3CCN(C)CC3)=C1)(C(C=CC=C4)=C4Br)=O.CS(=O)(O)=O
Molecular Formula
C23H32BrN3O9S3
Molecular Weight
670.61
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
5-HT2 Receptor;5-HT6 Receptor; MUC2
Available Sizes
Frequently Asked Questions
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