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Anti-Homeobox protein Hox-A4 HOXA4 Antibody Picoband®, PE Conjugate

Boster Bio Anti-Homeobox protein Hox-A4 HOXA4 Antibody catalog # PA1603. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

HOXA4 (HOMEOBOX A4), also known as HOX1D or HOMOLOG OF, is a protein that in humans is encoded by the HOXA4 gene, which is also part of the A cluster on chromosome 7. HOXA4 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.

Synonyms

Homeobox protein Hox-A4;Homeobox protein Hox-1.4;Homeobox protein Hox-1D;HOXA4;HOX1D;

Gene Name

Homeobox protein Hox-A4

UniProt

Q00056

Host

Rabbit

Reactivity

Rat,Mouse,Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human HOXA4, different from the related mouse sequence by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Embryonic nervous system.

Applications

IHC,ICC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT- 3'.

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

References & Citations

1. McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". 2. Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". 3. "Entrez Gene: HOXA4 homeobox A4".

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

34499 MW

Observed Molecular Weight

46 kDa

Fragment

Rabbit IgG

Specificity

No cross reactivity with other proteins.

Applications Notes

Immunocytochemistry , 0.5-1μg/ml, Human, -<br>Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat<br>Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse<br>

Subcellular Location

Nucleus.

Sequence Similarities

Belongs to the Antp homeobox family. Deformed subfamily.

Protein Name

Homeobox protein Hox-A4

Frequently Asked Questions

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