Anti-NR1/NDOR1 Antibody Picoband®, PE Conjugate

Boster Bio Anti-NR1/NDOR1 Antibody Picoband® catalog # A09352-1. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

NADPH-dependent diflavin oxidoreductase 1 is an enzyme that in humans is encoded by the NDOR1 gene. This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein catalyzes the transfer of electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants.

Synonyms

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

Gene Name

CD72 molecule

Gene ID

27158

UniProt

Q9UHB4

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NR1/NDOR1 recombinant protein (Position: R31-Q407).

Clonality

Polyclonal

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Applications

WB,ICC,IF,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Plays a role in B-cell proliferation and differentiation.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Kwasnicka, D. A., Krakowiak, A., Thacker, C., Brenner, C., Vincent, S. R. Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-ed hydrolase, DCS-1. J. Biol. Chem. 278: 39051-39058, 2003. 2. Kwasnicka-Crawford, D. A., Vincent, S. R. Role of a novel dual flavin reductase (NR1) and an associated histidine triad protein (DCS-1) in menadione-induced cytotoxicity. Biochem. Biophys. Res. Commun. 336: 565-571, 2005. 3. Paine, M. J. I., Garner, A. P., Powell, D., Sibbald, J., Sales, M., Pratt, N., Smith, T., Tew, D. G., Wolf, C. R. Cloning and characterization of a novel human dual flavin reductase. J. Biol. Chem. 275: 1471-1478, 2000.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

72 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/ml, -