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Anti-AP-B/RNPEP Antibody Picoband®, PE Conjugate

Boster Bio Anti-AP-B/RNPEP Antibody Picoband® catalog # A10683-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Aminopeptidase B is an enzyme that in humans is encoded by the RNPEP gene. Predicted to enable metalloaminopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular exosome.

Synonyms

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

Gene Name

NOVA alternative splicing regulator 2

Gene ID

6051

UniProt

Q9H4A4

Host

Rabbit

Reactivity

Human,Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human AP-B/RNPEP recombinant protein (Position: D66-K648).

Clonality

Polyclonal

Tissue Specificity

Brain. Expression restricted to astrocytes.

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Aurich-Costa, J., Cadel, S., Gouzy, C., Foulon, T., Cherif, D., Cohen, P. Assignment of the aminopeptidase B gene (RNPEP) to human chromosome 1 band q32 by in situ hybridization. Cytogenet. Cell Genet. 79: 143-144, 1997. 2. Cadel, S., Foulon, T., Viron, A., Balogh, A., Midol-Monnet, S., Noel, N., Cohen, P. Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase. Proc. Nat. Acad. Sci. 94: 2963-2968, 1997. 3. Cadel, S., Pierotti, A. R., Foulton, T., Creminon, C., Barre, N., Segretain, D., Cohen, P. Aminopeptidase-B in the rat testes: isolation, functional properties and cellular localization in the seminiferous tubules. Molec. Cell. Endocr. 110: 149-160, 1995.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

29370 MW

Observed Molecular Weight

73 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.25 μg/ml, Human, Mouse<br> Flow Cytometry (Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Subcellular Location

Nucleus.

Protein Name

Aquaporin-6

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