Anti-USP26 Antibody Picoband®, PE Conjugate

Boster Bio Anti-USP26 Antibody Picoband® catalog # A07732-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility.

Synonyms

Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

Gene Name

SRY-box 15

Gene ID

83844

UniProt

Q9BXU7

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human USP26 recombinant protein (Position: M1-K762).

Clonality

Polyclonal

Tissue Specificity

Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

Applications

WB,IHC,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Binds to the 5'-AACAAT-3' sequence.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Ma, Q., Li, Y., Guo, H., Li, C., Chen, J., Luo, M., Jiang, Z., Li, H., Gui, Y. A novel missense mutation in USP26 gene is associated with nonobstructive azoospermia. Reprod. Sci. 23: 1434-1441, 2016. 2. Ravel, C., El Houate, B., Chantot, S., Lourenco, D., Dumaine, A., Rouba, H., Bandyopadahyay, A., Radhakrishna, U., Das, B., Sengupta, S., Mandelbaum, J., Siffroi, J. P., McElreavey, K. Haplotypes, mutations and male fertility: the story of the testis-specific ubiquitin protease USP26. Molec. Hum. Reprod. 12: 643-646, 2006. 3. Stouffs, K., Lissens, W., Tournaye, H., Van Steirteghem, A., Liebaers, I. Possible role of USP26 in patients with severely impaired spermatogenesis. Europ. J. Hum. Genet. 13: 336-340, 2005.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

49229 MW

Observed Molecular Weight

104 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/ml, -