Anti-POLA2 Antibody Picoband®, PE Conjugate

Boster Bio Anti-POLA2 Antibody Picoband® catalog # A08427-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

DNA polymerase alpha subunit 2 is an enzyme that in humans is encoded by the POLA2 gene. POLA2 may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).

Synonyms

Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4; SERPINA4; KST; PI4

Gene Name

serpin family A member 4

Gene ID

23649

UniProt

Q14181

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human POLA2 recombinant protein (Position: N267-P579).

Clonality

Polyclonal

Tissue Specificity

Expressed by the liver and secreted in plasma.

Applications

ELISA,Flow Cytometry,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Ste Fa N, M. , L Agnès, Thomas, B. , Philippe, D. , Bertrand, G. , & Arnaud, M. , et al. (2009). Genetic polymorphisms in 85 dna repair genes and bladder cancer risk. Carcinogenesis, 30(5), 763-768. 2. Beausoleil, S., Villén, J., Gerber, S. et al. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nat Biotechnol 24, 1285–1292 (2006). 3. Stelzl, U. , Worm, U. , Lalowski, M. , Haenig, C. , Brembeck, F. H. , & Goehler, H. , et al. (2005). A human protein-protein interaction network: a resource for annotating the proteome. Cell, 122(6), 957-968.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.