Anti-Livin/Birc7 Antibody Picoband®, PE Conjugate

Boster Bio Anti-Livin/Birc7 Antibody Picoband® catalog # A02577-2. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Baculoviral IAP repeat-containing protein 7 is a protein that in humans is encoded by the BIRC7 gene. This protein is a member of the family of inhibitor of apoptosis proteins(IAP) and contains a single copy of a baculovirus IAP repeat(BIR) and a RING finger motif. Its gene is mapped to 20q13.3. It has got 280- and 298- amino acids. The protein is highly expressed in melanomas while lowly expressed in some lymphomas, fetal kidney, fetal liver, testis and thymus. BIRC7 plays a vital role in blocking apoptosis induced.

Synonyms

Tumor necrosis factor ligand superfamily member 4; OX40 ligand; OX40L; CD252; Tnfsf4; Ox40l; Txgp1l

Gene Name

tumor necrosis factor (ligand) superfamily, member 4

Gene ID

329581

UniProt

A2AWP0

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse Livin/Birc7 recombinant protein (Position: Q41-S285).

Clonality

Polyclonal

Tissue Specificity

Macrophages; peripheral blood leukocytes, lung, spleen and liver.

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Kasof GM, Gomes BC (May 2001). "Livin, a novel inhibitor of apoptosis protein family member". J Biol Chem 276 (5): 3238–46. 2. Lin JH, Deng G, Huang Q, Morser J (Feb 2001). "KIAP, a novel member of the inhibitor of apoptosis protein family". Biochem Biophys Res Commun 279 (3): 820–31. "Entrez Gene: BIRC7 baculoviral IAP repeat-containing 7 (livin)"

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.