Anti-GNAL Antibody Picoband®, PE Conjugate

Boster Bio Anti-GNAL Antibody Picoband® catalog # A09404-1. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Guanine nucleotide-binding protein G(olf) subunit alpha is a protein that in humans is encoded by the GNAL gene. This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants.

Synonyms

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

Gene Name

CD72 molecule

Gene ID

2774

UniProt

P38405

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human GNAL recombinant protein (Position: R114-H349).

Clonality

Polyclonal

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Applications

WB,IHC,ICC,IF,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Plays a role in B-cell proliferation and differentiation.

Components

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

References & Citations

1. Belluscio, L., Gold, G. H., Nemes, A., Axel, R. Mice deficient in G(olf) are anosmic. Neuron 20: 69-81, 1998. 2. Bressman, S. B., Heiman, G. A., Nygaard, T. G., Ozelius, L. J., Hunt, A. L., Brin, M. F., Gordon, M. F., Moskowitz, C. B., de Leon, D., Burke, R. E., Fahn, S., Risch, N. J., Beakefield, X. O., Kramer, P. L. A study of idiopathic torsion dystonia in a non-Jewish family: evidence for genetic heterogeneity. Neurology 44: 283-287, 1994. 3. Buck, L. B. Information coding in the mammalian olfactory system. Cold Spring Harbor Symp. Quant. Biol. 61: 147-155, 1996.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

44 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>