Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CHCHD10 Antibody Picoband®, PE Conjugate

Boster Bio Anti-CHCHD10 Antibody Picoband® catalog # A06312. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial, also known as Protein N27C7-4 is a protein that in humans is encoded by the CHCHD10 gene. This gene encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19.

Synonyms

ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1; ELAVL2; HUB

Gene Name

ELAV like RNA binding protein 2

Gene ID

400916

UniProt

Q8WYQ3

Host

Rabbit

Reactivity

Human,Monkey,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human CHCHD10 recombinant protein (Position: P80-P142).

Clonality

Polyclonal

Tissue Specificity

Brain; neural-specific.

Applications

ELISA,Flow Cytometry,IF,IHC,ICC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Function

Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.

Components

Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

References & Citations

1. Ajroud-Driss, S., Fecto, F., Ajroud, K., Lalani, I., Calvo, S. E., Mootha, V. K., Deng, H.-X., Siddique, N., Tahmoush, A. J., Heiman-Patterson, T. D., Siddique, T. Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy. Neurogenetics 16: 1-9, 2015. 2. Bannwarth, S., Ait-El-Mkadem, S., Chaussenot, A., Genin, E. C., Lacas-Gervais, S., Fragaki, K., Berg-Alonso, L., Kageyama, Y., Serre, V., Moore, D. G., Verschueren, A., Rouzier, C., and 11 others. A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement. Brain 137: 2329-2345, 2014. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 7/24/2014.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06312

Product MSDS

https://www.bosterbio.com/msds?sku=A06312

Calculated Molecular Weight

49655 MW

Observed Molecular Weight

15 kDa

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.25μg/ml, Human, Mouse, Rat, Monkey<br> Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5μg/ml, Human<br> Flow Cytometry (Fixed), 1-3μg/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5μg/ml, -<br>

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm.

Protein Name

AP-2 complex subunit mu

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Goose Cystatin 5 (CST5) ELISA Kit
MBS9348059 Inquire

Goose Cystatin 5 (CST5) ELISA Kit

Ask
View Details
CRH Antibody
51-101 0.25 mL

CRH Antibody

Ask
View Details
ZNF312B (FEZF1) (NM_001160264) Human Tagged ORF Clone Lentiviral Particle
RC228890L4V 200 µL

ZNF312B (FEZF1) (NM_001160264) Human Tagged ORF Clone Lentiviral Particle

Ask
View Details
Rabbit Polyclonal SPCS2 Antibody [Allophycocyanin]
NBP3-06490APC 0.1 mL

Rabbit Polyclonal SPCS2 Antibody [Allophycocyanin]

Ask
View Details
EXOC2 Rabbit pAb
E45R28058N-50 50 µL

EXOC2 Rabbit pAb

Ask
View Details
Anti-Phospho-BCAR1 (Y410) Rabbit Monoclonal Antibody
M00960Y410 100 μL/Vial

Anti-Phospho-BCAR1 (Y410) Rabbit Monoclonal Antibody

Ask
View Details