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Braftide

Braftide is an allosteric BRAF kinase inhibitor that disrupts dimer formation, targeting both wild-type and oncogenic variants like BRAFG469A. It suppresses MAPK signaling and inhibits proliferation in KRAS-mutant colorectal cancer cell lines such as HCT116 and HCT-15, making it a tool for studying oncogenic BRAF signaling in vitro.

Product Specifications

Field of Research

Signal Transduction

Molecular Weight

1243.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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