Braftide
Braftide is an allosteric BRAF kinase inhibitor that disrupts dimer formation, targeting both wild-type and oncogenic variants like BRAFG469A. It suppresses MAPK signaling and inhibits proliferation in KRAS-mutant colorectal cancer cell lines such as HCT116 and HCT-15, making it a tool for studying oncogenic BRAF signaling in vitro.
Product Specifications
Field of Research
Signal Transduction
Molecular Weight
1243.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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