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Anti-SFRP2 Antibody Picoband® (PE Conjugate)

Boster Bio Anti-SFRP2 Antibody Picoband® catalog # PB9362. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

SFRP2 is also known as FRP-2, SARP1 or SDF-5. It is Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.?

Synonyms

Secreted frizzled-related protein 2;FRP-2;sFRP-2;Secreted apoptosis-related protein 1;SARP-1;SFRP2;FRP2, SARP1;FKSG12, UNQ361/PRO697;

Gene Name

Secreted frizzled-related protein 2

UniProt

Q96HF1

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SFRP2 recombinant protein (Position: L104-C295). Human SFRP2?shares?99%?amino?acid?(aa)?sequence?identity?with mouse SFRP2.

Clonality

Polyclonal

Tissue Specificity

Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. .

Applications

ELISA,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, -<br>ELISA, 0.1-0.5μg/ml, -<br>

Subcellular Location

Secreted .

Sequence Similarities

Belongs to the secreted frizzled-related protein (sFRP) family.

Protein Name

Secreted frizzled-related protein 2

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