D-GsMTx4 TFA
D-GsMTx4 TFA is a selective peptide inhibitor of mechanosensitive Piezo2 and TRPC1/6 channels, blocking cationic stretch-activated channels. It reduces LPC-induced astrocyte toxicity and microglial reactivity and has demonstrated protective effects against myocardial ischemia-reperfusion injury in vivo, making it a valuable research tool for studying mechanotransduction in physiology and disease.
Product Specifications
Product Name Alternative
TRP Channel, TRPC6, TRPVChannel, TRPV Channel, TRPChannel, Piezo, Piezo Channel, PiezoChannel, D-GsMTx4 TFA, DGsMTx4TFA
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.29% (May vary between batches)
Solubility
DMSO:250 mg/mL (59.28 mM) ;10% DMSO+90% Saline:3.3 mg/mL (0.78 mM) ; H2O:36 mg/mL (8.54 mM)
Molecular Weight
4216.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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