Triclocarban

Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes[1][2][3].

Product Specifications

CAS Number

[101-20-2]

Product Name Alternative

3,4,4′-Trichlorocarbanilide

UNSPSC

12352005

Hazard Statement

H400, H410

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Triclocarban.html

Purity

98.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=CC=C(C=C1)NC(NC2=CC=C(C(Cl)=C2)Cl)=O

Molecular Formula

C13H9Cl3N2O

Molecular Weight

315.58

Precautions

H400, H410

References & Citations

[1]Kanbara Y, et al. Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress. J Toxicol Sci. 2013 Feb;38 (1) :49-55.|[2]Huang H, et al. The in vitro estrogenic activities of triclosan and triclocarban. J Appl Toxicol. 2014 Sep;34 (9) :1060-7.|[3]Kennedy RC, et al. Early life triclocarban exposure during lactation affects neonate rat survival. Reprod Sci. 2015 Jan;22 (1) :75-89.