Iberiotoxin TFA
Iberiotoxin (TFA) is a potent and selective blocker of large-conductance calcium-activated potassium (BK) channels, with a Kd of ~1 nM, while showing no effect on voltage-gated ion channels. This toxin is a valuable tool for studying BK channel function in neurobiology, smooth muscle physiology, and in models of hypertension and epilepsy, both in vitro and in vivo.
Product Specifications
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Molecular Weight
4230.85 (free base)
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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