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Iberiotoxin TFA

Iberiotoxin (TFA) is a potent and selective blocker of large-conductance calcium-activated potassium (BK) channels, with a Kd of ~1 nM, while showing no effect on voltage-gated ion channels. This toxin is a valuable tool for studying BK channel function in neurobiology, smooth muscle physiology, and in models of hypertension and epilepsy, both in vitro and in vivo.

Product Specifications

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Molecular Weight

4230.85 (free base)

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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