Noxiustoxin

Noxiustoxin, a peptide toxin from the Centruroides noxius scorpion venom, is a potent dual inhibitor of Kv1.3 (IC50 360 nM) and calcium-activated potassium channels. It serves as a critical pharmacological tool for studying potassium channel function and neuroinflammatory disease mechanisms in both cellular and animal models.