Dendrotoxin-I

Dendrotoxin-I is a potent neurotoxin isolated from Dendroaspis (mamba) snake venom that selectively inhibits voltage-gated potassium channels, specifically the KV1.1 and KV1.2 subunits. This high-affinity blocker is a valuable tool for studying potassium channel function and neuronal excitability in both in vitro electrophysiology and in vivo neuropharmacology research.