GSK106
GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199[1].
Product Specifications
CAS Number
[1652591-82-6]
UNSPSC
12352005
Target
Protein Arginine Deiminase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gsk106.html
Purity
98.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CC(N)CCC1)C2=CC=C3N=C(C(N4CC)=CC5=C4C=CC=C5)N(C)C3=C2.Cl
Molecular Formula
C24H28ClN5O
Molecular Weight
437.97
References & Citations
[1]Lewis HD, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar;11 (3) :189-91.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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