GSK106

GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199[1].

Product Specifications

CAS Number

[1652591-82-6]

UNSPSC

12352005

Target

Protein Arginine Deiminase

Type

Reference compound

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gsk106.html

Purity

98.28

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1CC(N)CCC1)C2=CC=C3N=C(C(N4CC)=CC5=C4C=CC=C5)N(C)C3=C2.Cl

Molecular Formula

C24H28ClN5O

Molecular Weight

437.97

References & Citations

[1]Lewis HD, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar;11 (3) :189-91.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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