Sipagladenant

Sipagladenant (Compound I) is an orally active adenosine receptor A2A inverse agonist[1]. Sipagladenant can be used in frontal lobe dysfunction research[2].

Product Specifications

CAS Number

[858979-50-7]

Product Name Alternative

KW-6356

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sipagladenant.html

Purity

99.68

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CN=C(C)C=C1)NC2=NC(C3=CC=CO3)=C(C(C4CCOCC4)=O)S2

Molecular Formula

C20H19N3O4S

Molecular Weight

397.45

References & Citations

[1]https://cdn.who.int/media/docs/default-source/international-nonproprietary-names- (inn) /pl127.pdf?sfvrsn=8544ca1e_3&download=true|[2]Horita, Takako. THERAPEUTIC AGENT FOR FRONTAL LOBE DYSFUNCTION, WO2016148308A1.