Mtb-IN-8
Mtb-IN-8 (compound 5jb) is an orally active inhibitor of Mycobacterium tuberculosis (Mtb) with MIC values of 0.03 μg/mL for H37Rv and 0.125-0.06 μg/mL for MDR-Mtb, respectively[1].
Product Specifications
CAS Number
[2549199-96-2]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mtb-in-8.html
Smiles
COC1=CC=C([C@@H]2C(C(NC(SCCC)=N3)=O)=C3NC(C2)=O)C([N+]([O-])=O)=C1
Molecular Formula
C17H18N4O5S
Molecular Weight
390.41
References & Citations
[1]Sun L, et al. Design, Synthesis, and Evaluation of the Antitubercular Activity of 5-Phenyl Substituted-5, 6-dihydropyrido[2, 3-d]pyrimidine-4, 7 (3H, 8H) -dione Compounds. J Med Chem. 2024 Sep 12;67 (17) :14927-14945.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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