Mtb-IN-8

Mtb-IN-8 (compound 5jb) is an orally active inhibitor of Mycobacterium tuberculosis (Mtb) with MIC values of 0.03 μg/mL for H37Rv and 0.125-0.06 μg/mL for MDR-Mtb, respectively[1].

Product Specifications

CAS Number

[2549199-96-2]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mtb-in-8.html

Smiles

COC1=CC=C([C@@H]2C(C(NC(SCCC)=N3)=O)=C3NC(C2)=O)C([N+]([O-])=O)=C1

Molecular Formula

C17H18N4O5S

Molecular Weight

390.41

References & Citations

[1]Sun L, et al. Design, Synthesis, and Evaluation of the Antitubercular Activity of 5-Phenyl Substituted-5, 6-dihydropyrido[2, 3-d]pyrimidine-4, 7 (3H, 8H) -dione Compounds. J Med Chem. 2024 Sep 12;67 (17) :14927-14945.