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π-TRTX-Hm3a

π-TRTX-Hm3a is a 37-residue peptide toxin from Heteroscodra maculata venom. It potently and selectively inhibits ASIC1a (IC50 1-2 nM) in a pH-dependent manner while potentiating ASIC1b (EC50 46.5 nM) . This tool is valuable for in vitro and in vivo studies of ASIC function in pain, ischemia, and neurological disorders.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Weight

4287.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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