π-TRTX-Hm3a
π-TRTX-Hm3a is a 37-residue peptide toxin from Heteroscodra maculata venom. It potently and selectively inhibits ASIC1a (IC50 1-2 nM) in a pH-dependent manner while potentiating ASIC1b (EC50 46.5 nM) . This tool is valuable for in vitro and in vivo studies of ASIC function in pain, ischemia, and neurological disorders.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Molecular Weight
4287.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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