GsAF-I

GsAF-I is a small molecule research compound that potently inhibits several voltage-gated sodium channels (Na_v 1.1-1.7) and the hERG1 potassium channel, with IC50 values ranging from nanomolar to low micromolar concentrations. This profile makes it a useful pharmacological tool for in vitro and in vivo studies of pain, epilepsy, and cardiac electrophysiology.