Eicosapentaenoyl serotonin

Eicosapentaenoyl serotonin (EPA-5-HT) is an N-acyl serotonin, a novel lipid present in the gut. Eicosapentaenoyl serotonin inhibits glucagon-like peptide-1 secretion and FAAH activity[1].

Product Specifications

CAS Number

[199875-71-3]

Product Name Alternative

EPA-5-HT

UNSPSC

12352005

Hazard Statement

H225, H319

Target

FAAH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/eicosapentaenoyl-serotonin.html

Concentration

21.71 mM * 100 μL in Ethanol

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)NCCC1=CNC2=CC=C(C=C12)O

Molecular Formula

C30H40N2O2

Molecular Weight

460.65

Precautions

H225, H319

References & Citations

[1]Verhoeckx KC, et al. Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract. Biochim Biophys Acta. 2011 Oct;1811 (10) :578-86.