Nemonoxacin (malate)

Nemonoxacin (TG-873870) malate is a nonfluorinated quinolone antibiotic. Nemonoxacin malate has broad-spectrum activity against Gram-positive, Gram-negative and atypical pathogens. Nemonoxacin malate can inhibit drug-resistant Streptococcus pneumoniae and Methicillin-resistant Staphylococcus aureus. Nemonoxacin malate can be used for the research of community-acquired pneumonia[1][2].

Product Specifications

CAS Number

[951163-60-3]

Product Name Alternative

TG-873870 (malate)

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nemonoxacin-malate.html

Purity

98.27

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)

Smiles

O=C(O)C(O)CC(O)=O.O=C(C1=CN(C2CC2)C3=C(C=CC(N4C[C@@H](N)C[C@H](C)C4)=C3OC)C1=O)O

Molecular Formula

C24H31N3O9

Molecular Weight

505.52

References & Citations

[1]Chotikanatis K, et al. In vitro activity of nemonoxacin, a novel nonfluorinated quinolone antibiotic, against Chlamydia trachomatis and Chlamydia pneumoniae. Antimicrob Agents Chemother. 2014;58 (3) :1800-1.|[2]Lai CC, et al. Nemonoxacin (TG-873870) for treatment of community-acquired pneumonia. Expert Rev Anti Infect Ther. 2014 Apr;12 (4) :401-17.