PIC1 PA

PIC1 PA is a 15-amino acid peptide analog that selectively inhibits classical complement pathway activation by binding to the C1q collagen-like region (KD ~33.3 nM), disrupting its interaction with the C1s-C1r-C1r-C1s/MASPs complex. This tool is valuable for in vitro studies of complement-driven pathologies and for researching therapeutic interventions in autoimmune and inflammatory diseases.