VPC-14228
Product Specifications
Product Name Alternative
21-desDFZ-d5,21-desDFZ
UNSPSC Description
VPC-14228 is a potent androgen receptor DNA binding domain (AR-DBD) inhibitor that interferes with the interaction of AR with androgen response elements and effectively blocks AR transcriptional activity. VPC-14228 can be used in prostate cancer research[1].
Target Antigen
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vpc-14228.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N1(C2=NC(C3=CC=CC=C3)=CS2)CCOCC1
Molecular Weight
246.33
References & Citations
[1]Kush Dalal, et al. Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer. J Biol Chem. 2014 Sep 19;289(38):26417-26429.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117669/VPC-14228-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117669/VPC-14228-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
19983-28-9
Available Sizes
Curated Selection
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