Apolipoprotein KV domain (67-77)
Apolipoprotein KV domain (67-77) is an 11-amino acid peptide identified from the KV domain of human apolipoprotein a (ApoA) with antiangiogenic and antitumor activities. Apolipoprotein KV domain (67-77) targets the angiogenic c-Src/ERK pathway by blocking activation signals received from vascular endothelial growth factor (VEGF) . Apolipoprotein KV domain (67-77) can be used in cancer research[1].
Product Specifications
CAS Number
515170-17-9
UNSPSC
12352209
Target
Apolipoprotein; VEGFR
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apolipoprotein-kv-domain-67-77.html
Smiles
O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CC=C(C=C3)O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CC=C(C=C4)O)N
Molecular Formula
C67H98N16O18S
Molecular Weight
1447.66
References & Citations
[1]Yi Z F, et al. A novel peptide from human apolipoprotein (a) inhibits angiogenesis and tumor growth by targeting c‐Src phosphorylation in VEGF‐induced human umbilical endothelial cells[J]. International Journal of Cancer, 2009, 124 (4) : 843-852.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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