(E) -Dehydrodiconiferyl alcohol
(E) -Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors[1]. And (E) -Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area[2].
Product Specifications
CAS Number
528814-97-3
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-dehydrodiconiferyl-alcohol.html
Solubility
10 mM in DMSO
Smiles
OCC1C2=CC(/C=C/CO)=CC(OC)=C2OC1C3=CC(OC)=C(C=C3)O
Molecular Formula
C20H22O6
Molecular Weight
358.39
References & Citations
[1]Costa G, et al. In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition. Antioxidants (Basel) . 2020;9 (9) :775. Published 2020 Aug 21.|[2]Hu X, et al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020;72 (2) :305-317.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CA IX; CA XII
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