Anti-INTS14 Antibody Picoband®, Dylight550 Conjugate

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

E.coli-derived human INTS14 recombinant protein (Position: R27-H271). Human INTS14 shares 99.2% and 98.4% amino acid (aa) sequence identity with mouse and rat INTS14, respectively.

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Pfleiderer, M. M. , & Galej, W. P. . (2021). Structure of the catalytic core of the integrator complex. Molecular Cell, 81(Suppl 1). 2. Beckedorff, F. , Blumenthal, E. , Dasilva, L. F. , Aoi, Y. , Cingaram, P. R. , & Yue, J. , et al. (2020). The human integrator complex facilitates transcriptional elongation by endonucleolytic cleavage of nascent transcripts. Cell Reports, 32(3). 3. Sabath, K. , Stubli, M. L. , Marti, S. , Leitner, A. , & Jonas, S. . (2020). Ints10–ints13–ints14 form a functional module of integrator that binds nucleic acids and the cleavage module. Nature Communications, 11(1).

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.