L-Palmitoylcarnitine (chloride)

L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].

Product Specifications

CAS Number

[18877-64-0]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-palmitoylcarnitine-chloride.html

Purity

99.93

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCC(O[C@H](CC(O)=O)C[N+](C)(C)C)=O.[Cl-]

Molecular Formula

C23H46ClNO4

Molecular Weight

436.07

Precautions

H315, H319, H335

References & Citations

[1]Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K (ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441 (2-3) :200-207.