MAO-A/SERT-IN-1
MAO-A/SERT-IN-1 is an inhibitor of MAO-A/serotonin transporter (SERT) . MAO-A/SERT-IN-1 can reduce SERT-mediated reuptake of 5-HT and has neuroprotective effects in cell inhibition models. MAO-A/SERT-IN-1 can improve depressive behavior in zebrafish and mice[1].
Product Specifications
CAS Number
3001361-38-9
UNSPSC
12352005
Target
Monoamine Oxidase; Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-a-sert-in-1.html
Smiles
O=C(C1=C2C3=NC=CC2=CC(OCCCO[N+]([O-])=O)=C1)C4=C3C=CC=C4
Molecular Formula
C19H14N2O5
Molecular Weight
350.32
References & Citations
[1]Zhong P, et al. Development of Nitric Oxide Releasing Oxoisoaporphines with Antidepressant Activities by Simultaneously Regulating MAO-A and SERT. J Med Chem. 2024 Sep 12;67 (17) :15509-15520.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A
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