Anti-CXCL2 Antibody Picoband® (Dylight550 Conjugate)

Boster Bio Anti-CXCL2 Antibody Picoband® catalog # PB9857. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Chemokine (C-X-C motif) ligand 2  (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha  (MIP2-alpha), Growth-regulated protein beta  (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.

Synonyms

C-X-C motif chemokine 2;Growth-regulated protein beta;Gro-beta;Macrophage inflammatory protein 2-alpha;MIP2-alpha;GRO-beta (5-73);GRO-beta-T;Hematopoietic synergistic factor;HSF;SB-251353;CXCL2;GRO2, GROB, MIP2A, SCYB2;

Gene Name

C-X-C motif chemokine 2

UniProt

P19875

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human CXCL2 recombinant protein (Position: T39-N107). Human CXCL2 shares 66.7% and 62.3% amino acid (aa) sequence identity with mouse and rat CXCL2, respectively.

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in osteoclasts (bones).

Applications

ELISA,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity. .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.