Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ATX2/ATXN2 Antibody Picoband® (Dylight550 Conjugate)

Selected Variant

PB9483-Dylight550

Size: 100 µg

Boster Bio Anti-ATX2/ATXN2 Antibody Picoband® catalog # PB9483. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Ataxin-2, the protein encoded by the ATXN2 gene, contains a polyglutamine tract, long expansions (greater than 33 repeats) of which result in spinocerebellar ataxia-2 (SCA2), an autosomal dominant form of olivopontocerebellar atrophy. The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. Ataxin-2 associates with L- and T-plastin and that overexpression of ataxin-2 leads to accumulation of T-plastin in mammalian cells.

Synonyms

Ataxin-2;Spinocerebellar ataxia type 2 protein;Trinucleotide repeat-containing gene 13 protein;ATXN2;ATX2, SCA2, TNRC13;

Gene Name

Ataxin-2

UniProt

Q99700

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ATX2, identical to the related mouse sequence.

Clonality

Polyclonal

Tissue Specificity

Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. .

Applications

IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, By Heat<br>

Subcellular Location

Cytoplasm .

Sequence Similarities

Belongs to the ATG14 family.

Protein Name

Ataxin-2

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

VCP Rabbit Polyclonal Antibody
ER30603 100 µL

VCP Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Anti-XIAP Antibody Picoband®, FITC Conjugate
PA1512-FITC 100 µg/Vial

Anti-XIAP Antibody Picoband®, FITC Conjugate

Sign In for Pricing
View Details
Anti-SCF/KITLG Antibody Picoband®, HRP Conjugate
PA1565-HRP 100 µg/Vial

Anti-SCF/KITLG Antibody Picoband®, HRP Conjugate

Sign In for Pricing
View Details
Anti-TMEM50B Antibody Picoband®, PE Conjugate
A14199-1-PE 100 µg/Vial

Anti-TMEM50B Antibody Picoband®, PE Conjugate

Sign In for Pricing
View Details
Anti-Protein S/PROS1 Antibody Picoband® (HRP Conjugate)
A01568-1-HRP 100 µg/Vial

Anti-Protein S/PROS1 Antibody Picoband® (HRP Conjugate)

Sign In for Pricing
View Details
Genomic DNA Isolation Kit-50p
24700 50 Preparations

Genomic DNA Isolation Kit-50p

Sign In for Pricing
View Details