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L-Valine-15N, d8

L-Valine-15N, d8 ((S) -Valine-15N, d8) is the deuterium and 15N labeled L-Valine. L-Valine ((S) -Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

Product Specifications

Product Name Alternative

(S) -Valine-15N, d8

UNSPSC

12352211

Target

Akt; Arginase; Bacterial; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

[15NH2][C@@](C(O)=O)([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

Molecular Formula

C5H3D8 15NO2

Molecular Weight

126.19

References & Citations

[1]Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074 (T) . Appl Microbiol Biotechnol. 2016 May;100 (10) :4627-36.|[2]Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.|[3]K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69 (4) :1283-6.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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