Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-IGFBP3 Antibody Picoband® (Dylight488 Conjugate)

Boster Bio Anti-IGFBP3 Antibody catalog # PA1498. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

Insulin-like growth factor-binding protein 3;IBP-3;IGF-binding protein 3;IGFBP-3;IGFBP3;IBP3;

Gene Name

Insulin-like growth factor-binding protein 3

UniProt

P17936

Host

Rabbit

Reactivity

Human,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human IGFBP-3.

Clonality

Polyclonal

Tissue Specificity

Expressed by most tissues. Present in plasma.

Applications

WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PA1498

Product MSDS

https://www.bosterbio.com/msds?sku=PA1498

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, Rat<br>

Subcellular Location

Secreted .

Sequence Similarities

Contains 1 IGFBP N-terminal domain.

Protein Name

Insulin-like growth factor-binding protein 3(IBP-3/IGF-binding protein 3/IGFBP-3)

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal Ficolin-2 Antibody (19) [DyLight 350]
NBP1-05042UV 0.1 mL

Mouse Monoclonal Ficolin-2 Antibody (19) [DyLight 350]

Ask
View Details
CNTN4 (NM_175612) Human Tagged Lenti ORF Clone
RC214500L1 10 µg

CNTN4 (NM_175612) Human Tagged Lenti ORF Clone

Ask
View Details
ZNF263 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
51393111 3 x 1.0 µg

ZNF263 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

Ask
View Details