Anti-IL-21/Il21 Antibody (Dylight488 Conjugate)

Boster Bio Anti-IL-21/Il21 Antibody Picoband® catalog # A00459-1. Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

Product Specifications

Background

Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

Beta-2-microglobulin; B2m

Gene Name

beta-2 microglobulin

UniProt

Q9ES17

Host

Rabbit

Reactivity

Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived mouse IL-21/Il21 recombinant protein (Position: H18-S146).

Clonality

Polyclonal

Tissue Specificity

Detected in lung, spleen, uterus, vagina and epididymis. .

Applications

IHC,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Function

Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.