Anti-IL10 Antibody (Dylight488 Conjugate)

Boster Bio Anti-IL10 Antibody Picoband® catalog # A00021-3. Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

Product Specifications

Background

Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.

Synonyms

Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10

Gene Name

interleukin 10

UniProt

P29456

Host

Rabbit

Reactivity

Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived rat IL10 recombinant protein (Position: K52-A170).

Clonality

Polyclonal

Tissue Specificity

Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.

Applications

ELISA,IHC

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Function

Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, Rat<br> ELISA, 0.1-0.5μg/ml,<br>

Subcellular Location

Secreted.

Protein Name

Receptor tyrosine-protein kinase erbB-2

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS7040252-01 0.02 mg

Recombinant Schizosaccharomyces pombe Uncharacterized protein C4B3.03c (SPCC4B3.03c)

Ask

View Details

MBS7040252-02 0.1 mg

Recombinant Schizosaccharomyces pombe Uncharacterized protein C4B3.03c (SPCC4B3.03c)

Ask

View Details

MBS7040252-03 5x 0.1 mg

Recombinant Schizosaccharomyces pombe Uncharacterized protein C4B3.03c (SPCC4B3.03c)

Ask

View Details

MBS7071390 Inquire

Recombinant Escherichia coli Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE (arnE), partial

Ask

View Details