Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CDK12 Antibody Picoband® (Dylight488 Conjugate)

Selected Variant

A03495-1-Dylight488

Size: 100 µg

Boster Bio Anti-CDK12 Antibody Picoband® catalog # A03495-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

CDK12 cyclin-dependent kinase 12 is a protein kinase that in humans is encoded by the CDK12 gene. This enzyme is a member of cyclin-dependent kinase protein family. CDK12 forms protein complexes with cyclin K (CCNK). The CDK12-CCNK complex acts at the level of RNA polymerase II (RNAPII) to regulate expression of long complex genes, several of which have roles in DNA maintenance and repair。

Synonyms

Calpain-2 catalytic subunit;3.4.22.53;Calcium-activated neutral proteinase 2;CANP 2;Calpain M-type;Calpain large polypeptide L2;Calpain-2 large subunit;Millimolar-calpain;M-calpain;CAPN2;CANPL2;

Gene Name

Calpain-2 catalytic subunit

UniProt

Q9NYV4

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human CDK12 recombinant protein (Position: Q1147-N1439).

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

ELISA,Flow Cytometry,IF,IHC,ICC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Function

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). .

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5μg/ml, Human<br> Immunohistochemistry, 2-5 μg/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5μg/ml, Human<br> Flow Cytometry(Fixed), 1-3μg/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5μg/ml, -<br>

Subcellular Location

Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca (2+) binding.

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mucin 3 (MUC3/1154), CF640R conjugate, 0.1mg/mL
BNC401154-100 1x 100 µL

Mucin 3 (MUC3/1154), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Cytokeratin 8/18 (B22.1 + B23.1), CF568 conjugate, 0.1mg/mL
BNC681221-100 1x 100 µL

Cytokeratin 8/18 (B22.1 + B23.1), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD55 Recombinant Rabbit Monoclonal Antibody [JE31-59]
HA722724 100 µL

CD55 Recombinant Rabbit Monoclonal Antibody [JE31-59]

Sign In for Pricing
View Details
Melanoma Marker (KBA.62), CF647 conjugate, 0.1mg/mL
BNC470895-500 1x 500 µL

Melanoma Marker (KBA.62), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Phospho-Histone H2A.X (S139) Recombinant Rabbit Monoclonal Antibody [SR33-09]
ET1602-2 100 µL

Phospho-Histone H2A.X (S139) Recombinant Rabbit Monoclonal Antibody [SR33-09]

Sign In for Pricing
View Details
Anti-TFEB Antibody Picoband®
A00662-4 100 µg/Vial

Anti-TFEB Antibody Picoband®

Sign In for Pricing
View Details