Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide
Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide is the drug-linker conjugate for ADC, containing ADC linker Gly-Mal-GGFG and ADC cytotoxin Deruxtecan 2-hydroxypropanamide[1].
Product Specifications
CAS Number
[2750623-07-3]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gly-mal-ggfg-deruxtecan-2-hydroxypropanamide.html
Purity
99.79
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OC(CNC[C@H](N1C(C=CC1=O)=O)C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C)C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C52H55FN10O15
Molecular Weight
1079.05
References & Citations
[1]Zhu Yi, et al. Camptothecin derivative and ligand-drug conjugate thereof. WO2022078260A1. 2021.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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