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Anti-Interferon gamma IFNG Antibody (Dylight488 Conjugate)

Boster Bio Anti-Interferon gamma IFNG Antibody Picoband® catalog # A00393-2. Tested in ELISA applications. This antibody reacts with Mouse.

Product Specifications

Background

Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.

Synonyms

Interferon gamma; IFN-gamma; IFNG

Gene Name

interferon gamma

UniProt

P01580

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived mouse <a href="https://www.bosterbio.com/anti-interferon-gamma-picoband-trade-antibody-a00393-1-boster.html" style="color:#EA8D28">Interferon gamma</a> recombinant protein (Position: M1-C155).

Clonality

Polyclonal

Tissue Specificity

Released primarily from activated T lymphocytes.

Applications

ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Applications Notes

ELISA Capture (Matched Antibody Pair), 2-8μg/ml<br>

Subcellular Location

Secreted.

Protein Name

Interferon gamma

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