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Anti-Glutathione Reductase/GSR Antibody Picoband® (Dylight488 Conjugate)

Boster Bio Anti-Glutathione Reductase/GSR Antibody Picoband® catalog # A01479-1. Tested in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Synonyms

Glutathione reductase, mitochondrial; GR; GRase; GSR; GLUR; GRD1

Gene Name

glutathione-disulfide reductase

UniProt

P00390

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).

Clonality

Polyclonal

Tissue Specificity

Expressed in peripheral blood leukocytes.

Applications

ELISA,IF,IHC-P,ICC,WB,Flow Cytometry

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Maintains high levels of reduced glutathione in the cytosol.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01479-1

Product MSDS

https://www.bosterbio.com/msds?sku=A01479-1

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml<br> Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml<br> Immunocytochemistry/Immunofluorescence, 5μg/ml<br> Flow Cytometry(Fixed), 1-3μg/1x10<sup>6</sup> cells<br> ELISA, 0.1-0.5μg/ml<br>

Subcellular Location

Isoform Mitochondrial: Mitochondrion.

Protein Name

Heterogeneous nuclear ribonucleoprotein A1

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