Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Munc18-1/STXBP1 Antibody Picoband® (Dylight488 Conjugate)

Boster Bio Anti-Munc18-1/STXBP1 Antibody Picoband® catalog # PB9819. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Syntaxin-binding protein 1, also known as Munc18-1, is a protein that in humans is encoded by the STXBP1 gene. By fluorescence in situ hybridization, the STXBP1 gene is mapped to chromosome 9q34.1. This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.

Synonyms

Syntaxin-binding protein 1;MUNC18-1;N-Sec1;Protein unc-18 homolog 1;Unc18-1;Protein unc-18 homolog A;Unc-18A;p67;STXBP1;UNC18A;

Gene Name

Syntaxin-binding protein 1

UniProt

P61764

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Munc18-1, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Brain and spinal cord. Highly enriched in axons.

Applications

Flow Cytometry,IF,IHC,ICC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PB9819

Product MSDS

https://www.bosterbio.com/msds?sku=PB9819

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat<br> Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br>

Subcellular Location

Cytoplasm, cytosol . Membrane; Peripheral membrane protein.

Protein Name

Syntaxin-binding protein 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Klhl11 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
25775114 3 x 1.0 µg

Klhl11 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

Ask
View Details
MEK Kinase 1 Lentiviral Activation Particles (h2)
sc-401107-LAC-2 200 µL

MEK Kinase 1 Lentiviral Activation Particles (h2)

Ask
View Details
HMBOX1 CRISPR Knock Out 293T Cell Line (Human)
23477141 1x10<sup>6</sup> cells/1.0ml

HMBOX1 CRISPR Knock Out 293T Cell Line (Human)

Ask
View Details
Rreb1 Mouse siRNA Oligo Duplex (Locus ID 68750)
SR422598 1 Kit

Rreb1 Mouse siRNA Oligo Duplex (Locus ID 68750)

Ask
View Details