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Sodium bicarbonate, for cell culture

Sodium bicarbonate, for cell culture (Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture) is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate, for cell culture can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort[1][2][3][4][5][6].

Product Specifications

CAS Number

144-55-8

Product Name Alternative

Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection

Field of Research

Others

Purity

99.0

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=[C]OO[NaH]

Molecular Formula

NaHCO3

Molecular Weight

84.01

Precautions

H302, H315, H319, H335

References & Citations

[1]Forsythe SM, et al. Sodium bicarbonate for the treatment of lactic acidosis. Chest. 2000 Jan;117 (1) :260-7.|[2]Corral L G, et al. Antimicrobial activity of sodium bicarbonate: A research note. Journal of food science, 1988, 53 (3) : 981-982.|[3]Kawakami T, et al. Sodium bicarbonate regulates nitric oxide production in mouse macrophage cell lines stimulated with lipopolysaccharide and interferon γ. Nitric Oxide. 2018 Sep 1;79:45-50.|[4]Robey IF, et al. Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer Res. 2009 Mar 15;69 (6) :2260-8.|[5]Wang Y, et al. Sodium bicarbonate, an inorganic salt and a potential active agent for cancer therapy. Chinese Chemical Letters, 2021, 32 (12) : 3687-3695.|[6]Lin J, et al. Sodium Bicarbonate Decreases Alcohol Consumption in Mice. Int J Mol Sci. 2024 May 3;25 (9) :5006.

Shipping Conditions

Room Temperature

Storage Conditions

RT, protect from light

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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